CUL9 rabbit pAb

  • Catalog No.：YT8105
  • Applications：IHC;WB
  • Reactivity：Human;Mouse
    • Target：
    • CUL9
    • Gene Name：
    • CUL9 H7AP1 KIAA0708 PARC
    • Protein Name：
    • Cullin-9 (CUL-9) (UbcH7-associated protein 1) (p53-associated parkin-like cytoplasmic protein)
    • Human Swiss Prot No：
    • Q8IWT3
    • Mouse Swiss Prot No：
    • Q80TT8
    • Immunogen：
    • Synthesized peptide derived from human C-ternal CUL9
    • Specificity：
    • This antibody detects endogenous levels of CUL9 at Human, Mouse
    • Formulation：
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500-2000 IHC 1:50-200
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Cullin-9 (CUL-9) (UbcH7-associated protein 1) (p53-associated parkin-like cytoplasmic protein)
    • Molecular Weight(Da)：
    • 277kD
    • Function：
    • Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 . Cytoplasmic anchor protein in p53/TP53-associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function .
    • Subcellular Location：
    • Cytoplasm .
    • Expression：
    • Ubiquitously expressed in all tissues with highest expression in testis brain and kidney.

    Attributes

    • Code：
    • YT8105
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 160 / 280 / 450
    • Delivery：
    • 2024-07-25
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