CTR2 rabbit pAb

  • Catalog No.：YT8091
  • Applications：IHC;WB
  • Reactivity：Human;Mouse;Rat
    • Target：
    • SLC7A2
    • Gene Name：
    • SLC7A2 ATRC2 CAT2
    • Protein Name：
    • Low affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (Solute carrier family 7 member 2)
    • Human Gene Id：
    • 6542
    • Human Swiss Prot No：
    • P52569
    • Mouse Swiss Prot No：
    • P18581
    • Immunogen：
    • Synthesized peptide derived from human C-ternal CTR2
    • Specificity：
    • This antibody detects endogenous levels of CTR2 at Human, Mouse,Rat
    • Formulation：
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500-2000 IHC 1:50-200
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Low affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (Solute carrier family 7 member 2)
    • Molecular Weight(Da)：
    • 72kD
    • Function：
    • Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing. Isoform 1 functions as permease that mediates the transport of the cationic amino acids (arginine, lysine and ornithine), and it has much higher affinity for arginine than isoform 2. Isoform 2 functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) . May play a role in classical or alternative activation of macrophages via its role in arginine transport.
    • Subcellular Location：
    • Cell membrane ; Multi-pass membrane protein .
    • Expression：
    • Expressed at high levels in the skeletal muscle, placenta and ovary. Expressed at intermediate levels in the liver and pancreas and at low levels in the kidney and heart.

    Attributes

    • Code：
    • YT8091
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 160 / 280 / 450
    • Delivery：
    • 2024-07-26
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