UBL4A rabbit pAb

  • Catalog No.：YT8081
  • Applications：IHC;WB
  • Reactivity：Human;Mouse;Rat
    • Target：
    • UBL4A
    • Gene Name：
    • UBL4A DXS254E GDX UBL4
    • Protein Name：
    • Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
    • Human Gene Id：
    • 8266
    • Human Swiss Prot No：
    • P11441
    • Mouse Swiss Prot No：
    • P21126
    • Immunogen：
    • Synthesized peptide derived from human N-ternal UBL4A
    • Specificity：
    • This antibody detects endogenous levels of UBL4A at Human, Mouse,Rat
    • Formulation：
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500-2000 IHC 1:50-200
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
    • Molecular Weight(Da)：
    • 17kD
    • Function：
    • As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation . The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum . Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome . Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the
    • Subcellular Location：
    • Cytoplasm, cytosol . Nucleus .

    Attributes

    • Code：
    • YT8081
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 160 / 280 / 450
    • Delivery：
    • 2024-07-25
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