PGK1 rabbit pAb
- Catalog No.:YT8080
- Applications:IHC;WB
- Reactivity:Human;Mouse;Rat
- Target:
- PGK1
- Gene Name:
- PGK1 PGKA MIG10 OK/SW-cl.110
- Protein Name:
- Phosphoglycerate kinase 1 (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2)
- Human Gene Id:
- 5230
- Human Swiss Prot No:
- P00558
- Mouse Gene Id:
- 18655
- Mouse Swiss Prot No:
- P09411
- Rat Gene Id:
- 24644
- Rat Swiss Prot No:
- P16617
- Immunogen:
- Synthesized peptide derived from human N-ternal PGK1
- Specificity:
- This antibody detects endogenous levels of PGK1 at Human, Mouse,Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000 IHC 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Phosphoglycerate kinase 1 (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2)
- Molecular Weight(Da):
- 46kD
- Function:
- Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate . In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) . May play a role in sperm motility .
- Subcellular Location:
- Cytoplasm.
- Expression:
- Mainly expressed in spermatogonia. Localized on the principle piece in the sperm (at protein level). Expression significantly decreased in the testis of elderly men.
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