PSM rabbit pAb

    • Catalog No.:YT7851
    • Applications:WB;IHC
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • PSM
      • Fields:
      • >>Alanine, aspartate and glutamate metabolism;>>Metabolic pathways;>>Vitamin digestion and absorption
      • Gene Name:
      • FOLH1 FOLH NAALAD1 PSM PSMA GIG27
      • Protein Name:
      • PSM
      • Human Gene Id:
      • 2346
      • Human Swiss Prot No:
      • Q04609
      • Mouse Swiss Prot No:
      • O35409
      • Immunogen:
      • Synthesized peptide derived from human PSM AA range: 571-620
      • Specificity:
      • This antibody detects endogenous levels of Human PSM
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • Glutamate carboxypeptidase 2 (EC 3.4.17.21;Cell growth-inhibiting gene 27 protein;Folate hydrolase 1;Folylpoly-gamma-glutamate carboxypeptidase;FGCP;Glutamate carboxypeptidase II;GCPII;Membrane glutamate carboxypeptidase;mGCP;N-acetylated-alpha-linked acidic dipeptidase I;NAALADase I;Prostate-specific membrane antigen;PSM;PSMA;Pteroylpoly-gamma-glutamate carboxypeptidase)
      • Molecular Weight(Da):
      • 83kD
      • Subcellular Location:
      • Cell membrane ; Single-pass type II membrane protein .; [Isoform PSMA']: Cytoplasm .
      • Expression:
      • Highly expressed in prostate epithelium. Detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). Detected in the small intestine, brain, kidney, liver, spleen, colon, trachea, spinal cord and the capillary endothelium of a variety of tumors. Expressed specifically in jejunum brush border membranes. In the brain, highly expressed in the ventral striatum and brain stem. Also expressed in fetal liver and kidney. Isoform PSMA' is the most abundant form in normal prostate. Isoform PSMA-1 is the most abundant form in primary prostate tumors. Isoform PSMA-3 is also found in normal prostate as well as in brain and liver. Isoform PSMA-9 is specifically expressed in prostate cancer.
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).