• Target：
• STXB2

• Gene Name：
• STXBP2 UNC18B

• Protein Name：
• STXB2

• Human Gene Id：
• 6813

• Human Swiss Prot No：
• Q15833

• Mouse Gene Id：
• 20911

• Mouse Swiss Prot No：
• Q64324

• Rat Gene Id：
• 81804

• Rat Swiss Prot No：
• Q62753

• Immunogen：
• Synthesized peptide derived from human STXB2 AA range: 392-442

• Specificity：
• This antibody detects endogenous levels of STXB2 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 65kD

• Background：
• This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2013],

• Function：
• function:Involved in the protein trafficking from the Golgi apparatus to the plasma membrane.,similarity:Belongs to the STXBP/unc-18/SEC1 family.,subunit:Binds syntaxins 1A, 2, 3 but not 4.,tissue specificity:Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.,

• Subcellular Location：
• cytosol,plasma membrane,integral component of membrane,apical plasma membrane,SNARE complex,specific granule,azurophil granule,zymogen granule membrane,cytolytic granule,extracellular exosome,tertiary granule,

• Expression：
• Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.

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