JADE3 rabbit pAb
- Catalog No.:YT7743
- Applications:WB;IHC
- Reactivity:Human;Mouse
- Target:
- JADE3
- Gene Name:
- PHF16 JADE3 KIAA0215
- Protein Name:
- JADE3
- Human Gene Id:
- 9767
- Human Swiss Prot No:
- Q92613
- Mouse Gene Id:
- 382207
- Mouse Swiss Prot No:
- Q6IE82
- Immunogen:
- Synthesized peptide derived from human JADE3 AA range: 484-534
- Specificity:
- This antibody detects endogenous levels of JADE3 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 91kD
- Background:
- This gene encodes a member of a family of large proteins containing PHD (plant homeo domain)-type zinc fingers. The encoded protein may be associated in a nuclear complex that functions in histone H4 acetylation. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013],
- Function:
- function:Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo.,induction:By estradiol in estrogen-responsive breast cancer cells.,similarity:Belongs to the JADE family.,similarity:Contains 1 PHD-type zinc finger.,subunit:Component of the HBO1 complex composed at least of ING4 or ING5, MYTS2/HBO1, EAF6, and one of PHF15, PHF16 and PHF17.,tissue specificity:Ubiquitously expressed, with highest levels in placenta and uterus.,
- Subcellular Location:
- histone acetyltransferase complex,
- Expression:
- Ubiquitously expressed, with highest levels in placenta and uterus.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).