QCR1 rabbit pAb
- Catalog No.:YT7734
- Applications:WB;ELISA;IHC
- Reactivity:Human;Mouse;Rat
- Target:
- QCR1
- Fields:
- >>Oxidative phosphorylation;>>Metabolic pathways;>>Cardiac muscle contraction;>>Thermogenesis;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy
- Gene Name:
- UQCRC1
- Protein Name:
- QCR1
- Human Gene Id:
- 7384
- Human Swiss Prot No:
- P31930
- Mouse Gene Id:
- 22273
- Mouse Swiss Prot No:
- Q9CZ13
- Rat Gene Id:
- 301011
- Rat Swiss Prot No:
- Q68FY0
- Immunogen:
- Synthesized peptide derived from human QCR1 AA range: 164-214
- Specificity:
- This antibody detects endogenous levels of QCR1 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 53kD
- Function:
- caution:Does not seem to have a protease activity as it lack the zinc-binding site.,function:This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.,similarity:Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.,subunit:The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).,
- Subcellular Location:
- Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
- Expression:
- Expressed in brain, including substantia nigra, striatum, cortex and cerebellum, and in spinal cord, heart, kidney, liver and muscle.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human uterus. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).