• Target：
• CSAD

• Fields：
• >>beta-Alanine metabolism;>>Taurine and hypotaurine metabolism;>>Pantothenate and CoA biosynthesis;>>Metabolic pathways

• Gene Name：
• CSAD CSD

• Protein Name：
• CSAD

• Human Gene Id：
• 51380

• Human Swiss Prot No：
• Q9Y600

• Mouse Gene Id：
• 246277

• Mouse Swiss Prot No：
• Q9DBE0

• Rat Gene Id：
• 60356

• Rat Swiss Prot No：
• Q64611

• Immunogen：
• Synthesized peptide derived from human CSAD AA range: 195-245

• Specificity：
• This antibody detects endogenous levels of CSAD at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 54kD

• Background：
• This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],

• Function：
• catalytic activity:3-sulfino-L-alanine = hypotaurine + CO(2).,cofactor:Pyridoxal phosphate.,pathway:Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 2/2.,similarity:Belongs to the group II decarboxylase family.,subunit:Homodimer.,

• Expression：
• Expressed in liver and brain. Also expressed in both astrocytes and neurons, but lower levels are expressed in astrocytes.

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