DB114 rabbit pAb

    • Catalog No.:YT7692
    • Applications:IHC;IF
    • Reactivity:Human
      • Target:
      • DB114
      • Gene Name:
      • DEFB114 DEFB14
      • Protein Name:
      • DB114
      • Human Swiss Prot No:
      • Q30KQ6
      • Immunogen:
      • Synthesized peptide derived from human DB114 AA range: 6-56
      • Specificity:
      • This antibody detects endogenous levels of DB114 at Human
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IHC 1:50-200. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 8kD
      • Background:
      • Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. The protein encoded by this gene is a beta-defensin with antimicrobial activity against E. coli, S. aureus, and C. albicans. The encoded protein also binds and neutralizes lipopolysaccharide (LPS), a factor involved in inflammatory diseases and male reproductive issues. [provided by RefSeq, Nov 2014],
      • Function:
      • function:Has antibacterial activity.,similarity:Belongs to the beta-defensin family.,
      • Subcellular Location:
      • Secreted .
      • Expression:
      • Expressed in epididymis, predominantly in the caput (at protein level).
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).