ROMO1 rabbit pAb
- Catalog No.:YT7645
- Applications:IHC;IF
- Reactivity:Human;Mouse
- Target:
- ROMO1
- Gene Name:
- ROMO1 C20orf52
- Protein Name:
- ROMO1
- Human Gene Id:
- 140823
- Human Swiss Prot No:
- P60602
- Mouse Gene Id:
- 67067
- Mouse Swiss Prot No:
- P60603
- Immunogen:
- Synthesized peptide derived from human ROMO1 AA range: 17-67
- Specificity:
- This antibody detects endogenous levels of ROMO1 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 9kD
- Background:
- The protein encoded by this gene is a mitochondrial membrane protein that is responsible for increasing the level of reactive oxygen species (ROS) in cells. The protein also has antimicrobial activity against a variety of bacteria by inducing bacterial membrane breakage. [provided by RefSeq, Nov 2014],
- Function:
- developmental stage:Expression increases in senescent cells.,function:Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence.,induction:By the anticancer drug fluorouracil (5FU).,miscellaneous:Enforced expression in IMR-90 cells leads to increased levels of ROS and induces premature cell senescence and nuclear DNA damage.,similarity:Belongs to the MGR2 family.,tissue specificity:Up-regulated in a number of cancer cell lines when compared to a normal lung fibroblast cell line.,
- Subcellular Location:
- Mitochondrion inner membrane ; Single-pass membrane protein .
- Expression:
- Up-regulated in a number of cancer cell lines when compared to a normal lung fibroblast cell line. Highly expressed in brain tumors.
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).