• Target：
• FBX17

• Gene Name：
• FBXO17 FBG4 FBX17 FBX26 FBXO26

• Protein Name：
• FBX17

• Human Gene Id：
• 115290

• Human Swiss Prot No：
• Q96EF6

• Mouse Gene Id：
• 50760

• Mouse Swiss Prot No：
• Q9QZM8

• Rat Gene Id：
• 292757

• Rat Swiss Prot No：
• Q6AY27

• Immunogen：
• Synthesized peptide derived from human FBX17 AA range: 61-111

• Specificity：
• This antibody detects endogenous levels of FBX17 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 31kD

• Background：
• This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

• Function：
• function:Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.,similarity:Contains 1 F-box domain.,similarity:Contains 1 FBA (F-box associated) domain.,subunit:Directly interacts with SKP1A and CUL1.,tissue specificity:Expressed in heart, skeletal muscle, liver and kidney. Expressed at lower levels in spleen and brain.,

• Subcellular Location：
• SCF ubiquitin ligase complex,

• Expression：
• Expressed in heart, skeletal muscle, liver and kidney. Expressed at lower levels in spleen and brain.

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