• Target：
• TRI11

• Gene Name：
• TRIM11 RNF92

• Protein Name：
• TRI11

• Human Gene Id：
• 81559

• Human Swiss Prot No：
• Q96F44

• Mouse Gene Id：
• 338364

• Mouse Swiss Prot No：
• Q99PQ2

• Rat Swiss Prot No：
• B1H278

• Immunogen：
• Synthesized peptide derived from human TRI11 AA range: 128-178

• Specificity：
• This antibody detects endogenous levels of TRI11 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 51kD

• Background：
• The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified. [provided by RefSeq, Jul 2008],

• Function：
• domain:The coiled-coil domain and the B30.2 domain are both necessary for interaction with humanin.,function:May have E3 ubiquitin ligase activity. May contribute to the regulation of the intracellular level of humanin or humanin-containing proteins through the proteasomal degradation pathway.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,subunit:Binds cytoplasmic tail of integrin alpha-1. Interacts with the humanin peptide.,tissue specificity:Ubiquitous.,

• Subcellular Location：
• Cytoplasm. Nucleus.

• Expression：
• Ubiquitous.

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