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- SELH rabbit pAb
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SELH rabbit pAb
- Catalog No.:YT7617
- Applications:WB
- Reactivity:Human;Mouse
- Immunogen:
- Synthesized peptide derived from human SELH AA range: 58-108
- Specificity:
- This antibody detects endogenous levels of SELH at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 13kD
- Background:
- This gene encodes a nucleolar protein, which belongs to the SelWTH family. It functions as an oxidoreductase, and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways, promote mitochondrial biogenesis and mitochondrial function, and suppress cellular senescence through genome maintenance and redox regulation. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2016],
- Function:
- function:May be involved in a redox-related process .,similarity:Belongs to the SelWTH family.,
![](/uploadfiles/PIC/YT7617wb-2019.jpg)
- Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night