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- MT1H rabbit pAb
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MT1H rabbit pAb
- Catalog No.:YT7601
- Applications:IHC;IF
- Reactivity:Human
- Fields:
- >>Mineral absorption
- Immunogen:
- Synthesized peptide derived from human MT1H AA range: 6-56
- Specificity:
- This antibody detects endogenous levels of MT1H at Human
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 7kD
- Function:
- domain:Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines.,function:Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.,similarity:Belongs to the metallothionein superfamily. Type 1 family.,subunit:Monomer.,
- Subcellular Location:
- nucleus,cytoplasm,perinuclear region of cytoplasm,
![](/uploadfiles/PIC/50-ihc-changai2207.jpg)
- Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).