• Target：
• RNF4

• Gene Name：
• RNF4 SNURF RES4-26

• Protein Name：
• RNF4

• Human Gene Id：
• 6047

• Human Swiss Prot No：
• P78317

• Mouse Gene Id：
• 19822

• Mouse Swiss Prot No：
• Q9QZS2

• Rat Gene Id：
• 29274

• Rat Swiss Prot No：
• O88846

• Immunogen：
• Synthesized peptide derived from human RNF4 AA range: 71-121

• Specificity：
• This antibody detects endogenous levels of RNF4 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 21kD

• Background：
• The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.[provided by RefSeq, Jul 2010],

• Function：
• function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with GSCL, Androgen receptor, TCF20, TBP and PATZ1.,tissue specificity:Widely expressed at low levels in many tissues; highly expressed in testis.,

• Subcellular Location：
• Cytoplasm. Nucleus. Nucleus, PML body. Nucleus, nucleoplasm.

• Expression：
• Widely expressed at low levels in many tissues; highly expressed in testis.

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