• Target：
• SLIB

• Fields：
• >>Neuroactive ligand-receptor interaction;>>Growth hormone synthesis, secretion and action

• Gene Name：
• GHRH GHRF

• Protein Name：
• SLIB

• Human Gene Id：
• 2691

• Human Swiss Prot No：
• P01286

• Mouse Gene Id：
• 14601

• Mouse Swiss Prot No：
• P16043

• Rat Gene Id：
• 29446

• Rat Swiss Prot No：
• P09916

• Immunogen：
• Synthesized peptide derived from human SLIB AA range: 43-93

• Specificity：
• This antibody detects endogenous levels of SLIB at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1：50-200. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 12kD

• Background：
• This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor, known as somatoliberin, which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016],

• Function：
• function:GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone.,online information:Growth hormone releasing hormone entry,pharmaceutical:Available under the names Groliberin (Pharmacia) or Somatrel (Ferring). Also available under the name Geref (Serono). Geref is a synthetic acetylated form of residues 1 to 29 of GHRH. Used for the treatment of growth hormone deficiency.,similarity:Belongs to the glucagon family.,

• Subcellular Location：
• Secreted.

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