• Target：
• AAAT

• Fields：
• >>Protein digestion and absorption;>>Central carbon metabolism in cancer

• Gene Name：
• SLC1A5 ASCT2 M7V1 RDR RDRC

• Protein Name：
• AAAT

• Human Gene Id：
• 6510

• Human Swiss Prot No：
• Q15758

• Mouse Swiss Prot No：
• P51912

• Immunogen：
• Synthesized peptide derived from human AAAT AA range: 345-395

• Specificity：
• This antibody detects endogenous levels of AAAT at Human/Mouse

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 60kD

• Background：
• The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011],

• Function：
• alternative products:A number of isoforms are produced by alternative initiation. Isoforms start at multiple alternative CUG and GUG codons,function:Has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. Act as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses.,similarity:Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,tissue specificity:Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein . Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

• Expression：
• Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.

A Preliminary Study on the Pathogenesis of Colorectal Cancer by Constructing a Hsa-circRNA-0067835-miRNA-mRNA Regulatory Network. OncoTargets and Therapy Oncotargets Ther. 2021; 14: 4645–4658 WB Human 1:1000 SW480 cell

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