U17L2 rabbit pAb

    • Catalog No.:YT7439
    • Applications:WB
    • Reactivity:Human;Mouse
      • Target:
      • U17L2
      • Gene Name:
      • USP17L2 DUB3
      • Protein Name:
      • U17L2
      • Human Swiss Prot No:
      • Q6R6M4
      • Mouse Swiss Prot No:
      • Q7M764
      • Immunogen:
      • Synthesized peptide derived from human U17L2 AA range: 321-371
      • Specificity:
      • This antibody detects endogenous levels of U17L2 at Human/Mouse
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 58kD
      • Background:
      • DUB3 is a member of the ubiquitin processing protease (UBP) subfamily of deubiquitinating enzymes. See USP1 (MIM 603478) for background information.[supplied by OMIM, Mar 2008],
      • Function:
      • catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,caution:The RS447 megasatellite DNA is a highly polymorphic conserved tandem repetitive sequence which contains a copy of USP17. It is present with an interindividual variation in copy number and between 20 to 103 copies can be found both on chromosome 4 and chromosome 8.,caution:The RS447 megasatellite DNA is a highly polymorphic conserved tandem repetitive sequence which contains a copy of USP17. It is present with an interindividual variation in copy number and between 20 to 103 copies can be found in the genome both on chromosome 4 and chromosome 8.,function:Functions in cell apoptosis. Cleaves ubiquitin fusion protein substrates.,function:Functions in cell apoptosis. Cleaves ubiquitin fusion protein substrates. May also bind hyaluronan and RNA.,induction:Up-regulated by interleukin-4 and interleukin-6 (
      • Subcellular Location:
      • Nucleus . Endoplasmic reticulum .
      • Expression:
      • Broadly expressed.
      • Products Images
      • Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night