SASH1 rabbit pAb

    • Catalog No.:YT7427
    • Applications:WB;IHC
    • Reactivity:Human;Mouse
      • Target:
      • SASH1
      • Gene Name:
      • SASH1 KIAA0790 PEPE1
      • Protein Name:
      • SASH1
      • Human Swiss Prot No:
      • O94885
      • Mouse Swiss Prot No:
      • P59808
      • Immunogen:
      • Synthesized peptide derived from human SASH1 AA range: 373-423
      • Specificity:
      • This antibody detects endogenous levels of SASH1 at Human/Mouse
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 137kD
      • Function:
      • function:May have a role in a signaling pathway. Could act as a tumor suppressor.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 SAM (sterile alpha motif) domains.,tissue specificity:Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues.,
      • Subcellular Location:
      • Cytoplasm .
      • Expression:
      • Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues. Expressed in the epidermis, epidermal keratinocytes, dermal fibroblasts and melanocytes (PubMed:23333244, PubMed:26203640).
      • Products Images
      • Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).