SASH1 rabbit pAb
- Catalog No.:YT7427
- Applications:WB;IHC
- Reactivity:Human;Mouse
- Target:
- SASH1
- Gene Name:
- SASH1 KIAA0790 PEPE1
- Protein Name:
- SASH1
- Human Gene Id:
- 23328
- Human Swiss Prot No:
- O94885
- Mouse Gene Id:
- 70097
- Mouse Swiss Prot No:
- P59808
- Immunogen:
- Synthesized peptide derived from human SASH1 AA range: 373-423
- Specificity:
- This antibody detects endogenous levels of SASH1 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 137kD
- Function:
- function:May have a role in a signaling pathway. Could act as a tumor suppressor.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 SAM (sterile alpha motif) domains.,tissue specificity:Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues.,
- Subcellular Location:
- Cytoplasm .
- Expression:
- Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues. Expressed in the epidermis, epidermal keratinocytes, dermal fibroblasts and melanocytes (PubMed:23333244, PubMed:26203640).
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).