• Target：
• AL1L1

• Fields：
• >>One carbon pool by folate;>>Metabolic pathways

• Gene Name：
• ALDH1L1 FTHFD

• Protein Name：
• AL1L1

• Human Gene Id：
• 10840

• Human Swiss Prot No：
• O75891

• Mouse Gene Id：
• 107747

• Mouse Swiss Prot No：
• Q8R0Y6

• Rat Gene Id：
• 64392

• Rat Swiss Prot No：
• P28037

• Immunogen：
• Synthesized peptide derived from human AL1L1 AA range: 512-562

• Specificity：
• This antibody detects endogenous levels of AL1L1 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 99kD

• Background：
• The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012],

• Function：
• catalytic activity:10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.,similarity:Belongs to the aldehyde dehydrogenase family.,similarity:Contains 1 acyl carrier domain.,similarity:In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.,similarity:In the N-terminal section; belongs to the GART family.,

• Subcellular Location：
• Cytoplasm, cytosol .

• Expression：
• Highly expressed in liver, pancreas and kidney.

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