D106A rabbit pAb

    • Catalog No.:YT7415
    • Applications:IHC;IF
    • Reactivity:Human
      • Target:
      • D106A
      • Gene Name:
      • DEFB106A BD6 DEFB106 DEFB6; DEFB106B
      • Protein Name:
      • D106A
      • Human Swiss Prot No:
      • Q8N104
      • Immunogen:
      • Synthesized peptide derived from human D106A AA range: 1-51
      • Specificity:
      • This antibody detects endogenous levels of D106A at Human
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IHC 1:50-200. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 7kD
      • Background:
      • Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106A, represents the more centromeric copy. [provided by RefSeq, Oct 2014],
      • Function:
      • function:Has antibacterial activity.,similarity:Belongs to the beta-defensin family.,tissue specificity:Expressed specifically in epididymis and lung.,
      • Subcellular Location:
      • Secreted . Membrane . Associates with tumor cell membrane-derived microvesicles (PubMed:23938203). .
      • Expression:
      • Expressed specifically in epididymis and lung.
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).