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- D106A rabbit pAb
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D106A rabbit pAb
- Catalog No.:YT7415
- Applications:IHC;IF
- Reactivity:Human
- Gene Name:
- DEFB106A BD6 DEFB106 DEFB6; DEFB106B
- Immunogen:
- Synthesized peptide derived from human D106A AA range: 1-51
- Specificity:
- This antibody detects endogenous levels of D106A at Human
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 7kD
- Background:
- Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106A, represents the more centromeric copy. [provided by RefSeq, Oct 2014],
- Function:
- function:Has antibacterial activity.,similarity:Belongs to the beta-defensin family.,tissue specificity:Expressed specifically in epididymis and lung.,
- Subcellular Location:
- Secreted . Membrane . Associates with tumor cell membrane-derived microvesicles (PubMed:23938203). .
- Expression:
- Expressed specifically in epididymis and lung.
![](/uploadfiles/PIC/197biantaoticc.jpg)
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).