• Target：
• HMGB3

• Gene Name：
• HMGB3 HMG2A HMG4

• Protein Name：
• HMGB3

• Human Gene Id：
• 3149

• Human Swiss Prot No：
• O15347

• Mouse Gene Id：
• 15354

• Mouse Swiss Prot No：
• O54879

• Immunogen：
• Synthesized peptide derived from human HMGB3 AA range: 123-173

• Specificity：
• This antibody detects endogenous levels of HMGB3 at Human/Mouse

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 22kD

• Background：
• This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

• Function：
• function:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains.,tissue specificity:Expressed predominantly in placenta.,

• Subcellular Location：
• Nucleus . Chromosome . Cytoplasm .

• Expression：
• Expressed predominantly in placenta.

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