TM55A rabbit pAb
- Catalog No.:YT7377
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- TM55A
- Fields:
- >>Phosphatidylinositol signaling system
- Gene Name:
- TMEM55A
- Protein Name:
- TM55A
- Human Gene Id:
- 55529
- Human Swiss Prot No:
- Q8N4L2
- Mouse Gene Id:
- 72519
- Mouse Swiss Prot No:
- Q9CZX7
- Rat Gene Id:
- 362490
- Rat Swiss Prot No:
- Q4V888
- Immunogen:
- Synthesized peptide derived from human TM55A AA range: 33-83
- Specificity:
- This antibody detects endogenous levels of TM55A at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 28kD
- Background:
- TMEM55A catalyzes the degradation of phosphatidylinositol 4,5-bisphosphate (PtdIns-4,5-P2) by removing the 4-phosphate (Ungewickell et al., 2005 [PubMed 16365287]).[supplied by OMIM, Mar 2008],
- Function:
- catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate.,catalytic activity:1-phosphatidyl-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate.,function:Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate.,tissue specificity:Ubiquitous.,
- Subcellular Location:
- Late endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, phagosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .
- Expression:
- Ubiquitous.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night