• Target：
• MMS19

• Gene Name：
• MMS19 MMS19L

• Protein Name：
• MMS19

• Human Gene Id：
• 64210

• Human Swiss Prot No：
• Q96T76

• Mouse Gene Id：
• 72199

• Mouse Swiss Prot No：
• Q9D071

• Immunogen：
• Synthesized peptide derived from human MMS19 AA range: 653-703

• Specificity：
• This antibody detects endogenous levels of MMS19 at Human/Mouse

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 113kD

• Function：
• function:May play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER-transcription factor TFIIH. May also function as a transcriptional coactivator of estrogen receptor (ER). May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types.,similarity:Belongs to the MET18/MMS19 family.,similarity:Contains 7 HEAT repeats.,subunit:Interacts with ERCC2/XPD, ERCC3/XPB and NCOA3/RAC3.,tissue specificity:Ubiquitously expressed with higher expression in testis.,

• Subcellular Location：
• Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . In mitosis, enriched on centrosomes during prophase, localizes to the spindle during metaphase and surrounds compacted spindle midzone microtubules during telophase. .

• Expression：
• Ubiquitously expressed with higher expression in testis.

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