NMRL1 rabbit pAb

    • Catalog No.:YT7264
    • Applications:WB
    • Reactivity:Human;Mouse;Rat
      • Target:
      • NMRL1
      • Gene Name:
      • NMRAL1 HSCARG
      • Protein Name:
      • NMRL1
      • Human Swiss Prot No:
      • Q9HBL8
      • Mouse Swiss Prot No:
      • Q8K2T1
      • Immunogen:
      • Synthesized peptide derived from human NMRL1 AA range: 179-229
      • Specificity:
      • This antibody detects endogenous levels of NMRL1 at Human/Mouse/Rat
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 33kD
      • Background:
      • This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015],
      • Function:
      • similarity:Belongs to the NmrA-type oxidoreductase family.,subunit:Homodimer; disulfide-linked.,
      • Subcellular Location:
      • Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Under normal redox growth conditions localizes in the cytoplasm and perinuclear region. Nuclear localization is promoted by increased intracellular nitric oxide and reduced NADPH/NADP(+) ratios.
      • Products Images
      • Western blot analysis of lysates from MDA-MB cells, primary antibody was diluted at 1:1000, 4°over night