NMRL1 rabbit pAb
- Catalog No.:YT7264
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- NMRL1
- Gene Name:
- NMRAL1 HSCARG
- Protein Name:
- NMRL1
- Human Gene Id:
- 57407
- Human Swiss Prot No:
- Q9HBL8
- Mouse Gene Id:
- 67824
- Mouse Swiss Prot No:
- Q8K2T1
- Rat Swiss Prot No:
- P86172
- Immunogen:
- Synthesized peptide derived from human NMRL1 AA range: 179-229
- Specificity:
- This antibody detects endogenous levels of NMRL1 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 33kD
- Background:
- This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015],
- Function:
- similarity:Belongs to the NmrA-type oxidoreductase family.,subunit:Homodimer; disulfide-linked.,
- Subcellular Location:
- Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Under normal redox growth conditions localizes in the cytoplasm and perinuclear region. Nuclear localization is promoted by increased intracellular nitric oxide and reduced NADPH/NADP(+) ratios.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from MDA-MB cells, primary antibody was diluted at 1:1000, 4°over night