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- AL1L2 rabbit pAb
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AL1L2 rabbit pAb
- Catalog No.:YT7251
- Applications:WB
- Reactivity:Human;Mouse
- Fields:
- >>One carbon pool by folate;>>Metabolic pathways
- Immunogen:
- Synthesized peptide derived from human AL1L2 AA range: 74-124
- Specificity:
- This antibody detects endogenous levels of AL1L2 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 102kD
- Background:
- This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010],
- Function:
- catalytic activity:10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.,sequence caution:Wrong choice of CDS.,similarity:Belongs to the aldehyde dehydrogenase family.,similarity:Contains 1 acyl carrier domain.,similarity:In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.,similarity:In the N-terminal section; belongs to the GART family.,
- Subcellular Location:
- Mitochondrion .
- Expression:
- Highly expressed in pancreas, heart, brain and skeletal muscle.
![](/uploadfiles/PIC/YT7251wb-2019.jpg)
- Western blot analysis of lysates from Jurkat cells, primary antibody was diluted at 1:1000, 4°over night