RDH14 rabbit pAb

    • Catalog No.:YT7225
    • Applications:WB;ELISA;IHC
    • Reactivity:Human;Mouse
      • Target:
      • RDH14
      • Gene Name:
      • RDH14 PAN2 UNQ529/PRO1072
      • Protein Name:
      • RDH14
      • Human Swiss Prot No:
      • Q9HBH5
      • Mouse Swiss Prot No:
      • Q9ERI6
      • Immunogen:
      • Synthesized peptide derived from human RDH14 AA range: 283-333
      • Specificity:
      • This antibody detects endogenous levels of RDH14 at Human/Mouse
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 37kD
      • Function:
      • catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Magnesium.,enzyme regulation:Activated by ADP.,function:Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels.,function:Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. No steroid dehydrogenase activity detected.,similarity:Belongs to the 5'-nucleotidase type 3 family.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,tissue specificity:Expressed in brain, kidney, pancreas and placenta.,tissue specificity:Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.,
      • Subcellular Location:
      • nucleus,mitochondrion,lysosomal membrane,endoplasmic reticulum,endoplasmic reticulum membrane,membrane,
      • Expression:
      • Widely expressed.
      • Products Images
      • Western blot analysis of lysates from MDA-MB cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).