HERC3 rabbit pAb

    • Catalog No.：YT7201
    • Applications：WB
    • Reactivity：Human
      • Target：
      • HERC3
      • Fields：
      • >>Ubiquitin mediated proteolysis
      • Gene Name：
      • HERC3 KIAA0032
      • Protein Name：
      • HERC3
      • Human Gene Id：
      • 8916
      • Human Swiss Prot No：
      • Q15034
      • Immunogen：
      • Synthesized peptide derived from human HERC3 AA range: 985-1035
      • Specificity：
      • This antibody detects endogenous levels of HERC3 at Human
      • Formulation：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source：
      • Polyclonal, Rabbit,IgG
      • Dilution：
      • WB 1：500-2000
      • Purification：
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration：
      • 1 mg/ml
      • Storage Stability：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da)：
      • 116kD
      • Background：
      • This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012],
      • Function：
      • function:E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.,pathway:Protein modification; protein ubiquitination.,PTM:Ubiquitinated; which promotes degradation by the proteasome.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 7 RCC1 repeats.,subcellular location:Also found in vesicular-like structures.,
      • Subcellular Location：
      • Cytoplasm. Cytoplasmic vesicle. Also found in vesicular-like structures.
      • Products Images
      • Western blot analysis of lysates from 3T3 cells, primary antibody was diluted at 1:1000, 4°over night

      Attributes

      • Code：
      • YT7201
      • Size
      • 40μL / 100μL / 200μL
      • Price$：
      • 150 / 280 / 450
      • Delivery：
      • 2024-09-02
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