• Target：
• QOR

• Gene Name：
• CRYZ

• Protein Name：
• QOR

• Human Gene Id：
• 1429

• Human Swiss Prot No：
• Q08257

• Mouse Gene Id：
• 12972

• Mouse Swiss Prot No：
• P47199

• Rat Gene Id：
• 362061

• Rat Swiss Prot No：
• Q6AYT0

• Immunogen：
• Synthesized peptide derived from human QOR AA range: 275-325

• Specificity：
• This antibody detects endogenous levels of QOR at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 36kD

• Background：
• Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008],

• Function：
• catalytic activity:NADPH + 2 quinone = NADP(+) + 2 semiquinone.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones are the best substrates. May act in the detoxification of xenobiotics.,similarity:Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.,subunit:Homotetramer.,tissue specificity:Only very low amounts in the lens.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Only very low amounts in the lens.

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