• Target：
• KRA33

• Gene Name：
• KRTAP3-3 KAP3.3 KRTAP3.3

• Protein Name：
• KRA33

• Human Gene Id：
• 85293

• Human Swiss Prot No：
• Q9BYR6

• Mouse Swiss Prot No：
• Q9D7P0

• Immunogen：
• Synthesized peptide derived from human KRA33 AA range: 35-85

• Specificity：
• This antibody detects endogenous levels of KRA33 at Human/Mouse

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1：50-200. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 11kD

• Background：
• This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008],

• Function：
• function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 3 family.,subunit:Interacts with hair keratins.,tissue specificity:Localized to the upper cortex of the hair shaft.,

• Subcellular Location：
• keratin filament,

• Expression：
• Localized to the upper cortex of the hair shaft.

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