KRA33 rabbit pAb
- Catalog No.:YT7149
- Applications:IHC;IF
- Reactivity:Human;Mouse
- Target:
- KRA33
- Gene Name:
- KRTAP3-3 KAP3.3 KRTAP3.3
- Protein Name:
- KRA33
- Human Gene Id:
- 85293
- Human Swiss Prot No:
- Q9BYR6
- Mouse Swiss Prot No:
- Q9D7P0
- Immunogen:
- Synthesized peptide derived from human KRA33 AA range: 35-85
- Specificity:
- This antibody detects endogenous levels of KRA33 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 11kD
- Background:
- This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008],
- Function:
- function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 3 family.,subunit:Interacts with hair keratins.,tissue specificity:Localized to the upper cortex of the hair shaft.,
- Subcellular Location:
- keratin filament,
- Expression:
- Localized to the upper cortex of the hair shaft.
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).