CNOT6 rabbit pAb
- Catalog No.:YT7096
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- CNOT6
- Fields:
- >>RNA degradation
- Gene Name:
- CNOT6 CCR4 KIAA1194
- Protein Name:
- CNOT6
- Human Gene Id:
- 57472
- Human Swiss Prot No:
- Q9ULM6
- Mouse Gene Id:
- 104625
- Mouse Swiss Prot No:
- Q8K3P5
- Rat Gene Id:
- 287249
- Rat Swiss Prot No:
- Q6AXU9
- Immunogen:
- Synthesized peptide derived from human CNOT6 AA range: 293-343
- Specificity:
- This antibody detects endogenous levels of CNOT6 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 61kD
- Background:
- This gene encodes the catalytic component of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates. The CCR4-NOT complex plays a role in many cellular processes, including miRNA-mediated repression, mRNA degradation, and transcriptional regulation. [provided by RefSeq, Dec 2014],
- Function:
- cofactor:Magnesium.,function:Poly(A) nuclease involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. Has 3'-5' RNase activity. The CCR4-NOT complex functions as general transcription regulation complex.,similarity:Belongs to the CCR4/nocturin family.,similarity:Contains 3 LRR (leucine-rich) repeats.,subunit:Subunit of the CCR4-NOT core complex that contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8. Interacts with UNR.,
- Subcellular Location:
- Cytoplasm . Nucleus . Predominantly cytoplasmic. .
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night