• Target：
• METK2

• Fields：
• >>Cysteine and methionine metabolism;>>Metabolic pathways;>>Biosynthesis of amino acids;>>Biosynthesis of cofactors

• Gene Name：
• MAT2A AMS2 MATA2

• Protein Name：
• METK2

• Human Gene Id：
• 4144

• Human Swiss Prot No：
• P31153

• Mouse Gene Id：
• 232087

• Mouse Swiss Prot No：
• Q3THS6

• Rat Gene Id：
• 171347

• Rat Swiss Prot No：
• P18298

• Immunogen：
• Synthesized peptide derived from human METK2 AA range: 294-344

• Specificity：
• This antibody detects endogenous levels of METK2 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 43kD

• Background：
• The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011],

• Function：
• catalytic activity:ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L-methionine.,cofactor:Binds 1 potassium ion per subunit.,cofactor:Binds 2 divalent ions per subunit. Magnesium or cobalt.,function:Catalyzes the formation of S-adenosylmethionine from methionine and ATP.,pathway:Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.,PTM:The alpha' subunit is a post-translationally modified version of MAT2A.,similarity:Belongs to the AdoMet synthetase family.,subunit:Heterotetramer composed of 2 catalytic alpha subunits (alpha and alpha') (MAT2A) and 1 copy of beta subunit (MAT2B).,

• Subcellular Location：
• cytosol,methionine adenosyltransferase complex,

• Expression：
• Detected in kidney.

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