• Target：
• TTYH2

• Gene Name：
• TTYH2 C17orf29

• Protein Name：
• TTYH2

• Human Gene Id：
• 94015

• Human Swiss Prot No：
• Q9BSA4

• Mouse Gene Id：
• 117160

• Mouse Swiss Prot No：
• Q3TH73

• Immunogen：
• Synthesized peptide derived from human TTYH2 AA range: 319-369

• Specificity：
• This antibody detects endogenous levels of TTYH2 at Human/Mouse

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 59kD

• Background：
• This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel, and may play a role in kidney tumorigenesis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

• Function：
• function:Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation.,similarity:Belongs to the tweety family.,tissue specificity:Expressed at higher level in brain and testis and at lower levels in heart, ovary, spleen and peripheral blood leukocytes. Up-regulated in 13 of 16 renal cell carcinoma samples examined. Up-regulated in colon carcinoma.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Expressed at higher level in brain and testis and at lower levels in heart, ovary, spleen and peripheral blood leukocytes. Up-regulated in 13 of 16 renal cell carcinoma samples examined. Up-regulated in colon carcinoma.

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