PHLP2 rabbit pAb

    • Catalog No.:YT6991
    • Applications:WB;IHC
    • Reactivity:Human;Mouse
      • Target:
      • PHLP2
      • Fields:
      • >>PI3K-Akt signaling pathway
      • Gene Name:
      • PHLPP2 KIAA0931 PHLPPL
      • Protein Name:
      • PHLP2
      • Human Swiss Prot No:
      • Q6ZVD8
      • Mouse Swiss Prot No:
      • Q8BXA7
      • Immunogen:
      • Synthesized peptide derived from human PHLP2 AA range: 381-431
      • Specificity:
      • This antibody detects endogenous levels of PHLP2 at Human/Mouse
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 146kD
      • Subcellular Location:
      • Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. In colorectal cancer tissue, expression is concentrated in the cytoplasm and nucleus.
      • Expression:
      • In colorectal cancer tissue, expression is highest in the surface epithelium of normal colonic mucosa adjacent to the cancer tissue but is largely excluded from the crypt bases. Expression is lost or significantly decreased in 80% of tested tumors (at protein level).
      • Products Images
      • Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).