DET1 rabbit pAb

    • Catalog No.:YT6984
    • Applications:WB
    • Reactivity:Human;Mouse
      • Target:
      • DET1
      • Fields:
      • >>Ubiquitin mediated proteolysis
      • Gene Name:
      • DET1
      • Protein Name:
      • DET1
      • Human Swiss Prot No:
      • Q7L5Y6
      • Mouse Swiss Prot No:
      • Q9D0A0
      • Immunogen:
      • Synthesized peptide derived from human DET1 AA range: 48-98
      • Specificity:
      • This antibody detects endogenous levels of DET1 at Human/Mouse
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 61kD
      • Function:
      • function:Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation.,similarity:Belongs to the DET1 family.,subunit:Component of the DCX DET1-COP1 ubiquitin ligase complex at least composed of RBX1, DET1, DDB1, CUL4A and COP1.,tissue specificity:Highly expressed in the ovary, some lymphoid organs and resting leukocytes.,
      • Subcellular Location:
      • Nucleus .
      • Expression:
      • Highly expressed in the ovary, some lymphoid organs and resting leukocytes.
      • Products Images
      • Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night