SNX17 rabbit pAb
- Catalog No.:YT6969
- Applications:WB;IHC
- Reactivity:Human;Mouse;Rat
- Target:
- SNX17
- Gene Name:
- SNX17 KIAA0064
- Protein Name:
- SNX17
- Human Gene Id:
- 9784
- Human Swiss Prot No:
- Q15036
- Mouse Gene Id:
- 266781
- Mouse Swiss Prot No:
- Q8BVL3
- Rat Gene Id:
- 298836
- Rat Swiss Prot No:
- Q6AYS6
- Immunogen:
- Synthesized peptide derived from human SNX17 AA range: 398-448
- Specificity:
- This antibody detects endogenous levels of SNX17 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 52kD
- Background:
- This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012],
- Function:
- domain:The PX domain is required for association with endosomes.,function:May be involved in protein trafficking.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 1 Ras-associating domain.,subcellular location:Associated with early endosomes.,subunit:Interacts with the C-termini of P-selectin, PTC, LDLR, VLDLR, LRP1 and LRP8.,
- Subcellular Location:
- Cytoplasm . Early endosome . Cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side .
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).