• Target：
• SNX17

• Gene Name：
• SNX17 KIAA0064

• Protein Name：
• SNX17

• Human Gene Id：
• 9784

• Human Swiss Prot No：
• Q15036

• Mouse Gene Id：
• 266781

• Mouse Swiss Prot No：
• Q8BVL3

• Rat Gene Id：
• 298836

• Rat Swiss Prot No：
• Q6AYS6

• Immunogen：
• Synthesized peptide derived from human SNX17 AA range: 398-448

• Specificity：
• This antibody detects endogenous levels of SNX17 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 52kD

• Background：
• This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012],

• Function：
• domain:The PX domain is required for association with endosomes.,function:May be involved in protein trafficking.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 1 Ras-associating domain.,subcellular location:Associated with early endosomes.,subunit:Interacts with the C-termini of P-selectin, PTC, LDLR, VLDLR, LRP1 and LRP8.,

• Subcellular Location：
• Cytoplasm . Early endosome . Cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side .

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