TXND8 rabbit pAb

    • Catalog No.:YT6952
    • Applications:WB
    • Reactivity:Human;Mouse;Rat
      • Target:
      • TXND8
      • Gene Name:
      • TXNDC8 SPTRX3 TRX6
      • Protein Name:
      • TXND8
      • Human Swiss Prot No:
      • Q6A555
      • Mouse Swiss Prot No:
      • Q69AB2
      • Immunogen:
      • Synthesized peptide derived from human TXND8 AA range: 64-114
      • Specificity:
      • This antibody detects endogenous levels of TXND8 at Human/Mouse/Rat
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 14kD
      • Function:
      • function:May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm.,miscellaneous:Increased levels, possibly caused by overexpression, are observed in morphologically abnormal spermatozoa from infertile men, suggesting that it may be used as a marker of aberrant spermatogenesis.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level).,
      • Subcellular Location:
      • Cytoplasm . Golgi apparatus .
      • Expression:
      • Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level).
      • Products Images
      • Western blot analysis of lysates from Jurkat cells, primary antibody was diluted at 1:1000, 4°over night