• Target：
• PO2F3

• Fields：
• >>Herpes simplex virus 1 infection;>>Lipid and atherosclerosis

• Gene Name：
• POU2F3 OTF11 PLA1

• Protein Name：
• PO2F3

• Human Gene Id：
• 25833

• Human Swiss Prot No：
• Q9UKI9

• Mouse Swiss Prot No：
• P31362

• Rat Swiss Prot No：
• P42571

• Immunogen：
• Synthesized peptide derived from human PO2F3 AA range: 240-290

• Specificity：
• This antibody detects endogenous levels of PO2F3 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 48kD

• Background：
• This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],

• Function：
• function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Regulated the expression of a number of genes such as SPRR2A or placental lactogen.,similarity:Belongs to the POU transcription factor family. Class-2 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,tissue specificity:Specifically expressed in epidermis and cultured keratinocytes.,

• Subcellular Location：
• Nucleus.

• Expression：
• Specifically expressed in epidermis and cultured keratinocytes.

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