KR105 rabbit pAb
- Catalog No.:YT6913
- Applications:WB;ELISA;IHC
- Reactivity:Human
- Target:
- KR105
- Gene Name:
- KRTAP10-5 KAP10.5 KAP18-5 KRTAP10.5 KRTAP18-5 KRTAP18.5
- Protein Name:
- KR105
- Human Gene Id:
- 386680
- Human Swiss Prot No:
- P60370
- Immunogen:
- Synthesized peptide derived from human KR105 AA range: 88-138
- Specificity:
- This antibody detects endogenous levels of KR105 at Human
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 30kD
- Background:
- This is an intronless gene located in a cluster of related genes on the q arm of chromosome 21. The proteins encoded by these genes form disulfide bonds with cysteine residues in hair keratins, thereby contributing to the structure and stability of hair fibers. [provided by RefSeq, Apr 2014],
- Function:
- function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 10 family.,subunit:Interacts with hair keratins.,tissue specificity:Restricted to a narrow region of the hair fibre cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues.,
- Subcellular Location:
- keratin filament,
- Expression:
- Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues.
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- Antibody-FAQs
- Products Images
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