EIF3I rabbit pAb
- Catalog No.:YT6871
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- EIF3I
- Gene Name:
- EIF3I EIF3S2 TRIP1
- Protein Name:
- EIF3I
- Human Gene Id:
- 8668
- Human Swiss Prot No:
- Q13347
- Mouse Gene Id:
- 54709
- Mouse Swiss Prot No:
- Q9QZD9
- Rat Gene Id:
- 682390
- Rat Swiss Prot No:
- B0BNA7
- Immunogen:
- Synthesized peptide derived from human EIF3I AA range: 100-150
- Specificity:
- This antibody detects endogenous levels of EIF3I at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 36kD
- Function:
- function:Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.,mass spectrometry: PubMed:17322308,mass spectrometry: PubMed:18599441,PTM:Phosphorylated by TGF-beta type II receptor.,similarity:Belongs to the eIF-3 subunit I family.,similarity:Contains 5 WD repeats.,subunit:Component of the eukaryotic
- Subcellular Location:
- Cytoplasm .
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night