PLP2 rabbit pAb
- Catalog No.:YT6863
- Applications:WB;ELISA;IHC
- Reactivity:Human;Mouse;Rat
- Target:
- PLP2
- Gene Name:
- PLP2 A4
- Protein Name:
- PLP2
- Human Gene Id:
- 5355
- Human Swiss Prot No:
- Q04941
- Mouse Gene Id:
- 18824
- Mouse Swiss Prot No:
- Q9R1Q7
- Rat Gene Id:
- 302562
- Rat Swiss Prot No:
- Q6P742
- Immunogen:
- Synthesized peptide derived from human PLP2 AA range: 56-106
- Specificity:
- This antibody detects endogenous levels of PLP2 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 17kD
- Background:
- This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked mental retardation. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010],
- Function:
- function:May play a role in cell differentiation in the intestinal epithelium.,similarity:Contains 1 MARVEL domain.,tissue specificity:Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt.,
- Subcellular Location:
- Membrane; Multi-pass membrane protein.
- Expression:
- Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt.
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