• Target：
• PLP2

• Gene Name：
• PLP2 A4

• Protein Name：
• PLP2

• Human Gene Id：
• 5355

• Human Swiss Prot No：
• Q04941

• Mouse Gene Id：
• 18824

• Mouse Swiss Prot No：
• Q9R1Q7

• Rat Gene Id：
• 302562

• Rat Swiss Prot No：
• Q6P742

• Immunogen：
• Synthesized peptide derived from human PLP2 AA range: 56-106

• Specificity：
• This antibody detects endogenous levels of PLP2 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 17kD

• Background：
• This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked mental retardation. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010],

• Function：
• function:May play a role in cell differentiation in the intestinal epithelium.,similarity:Contains 1 MARVEL domain.,tissue specificity:Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt.,

• Subcellular Location：
• Membrane; Multi-pass membrane protein.

• Expression：
• Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt.

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