EI24 rabbit pAb
- Catalog No.:YT6836
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- EI24
- Fields:
- >>p53 signaling pathway
- Gene Name:
- EI24 PIG8
- Protein Name:
- EI24
- Human Gene Id:
- 9538
- Human Swiss Prot No:
- O14681
- Mouse Gene Id:
- 13663
- Mouse Swiss Prot No:
- Q61070
- Rat Gene Id:
- 300514
- Rat Swiss Prot No:
- Q4KM77
- Immunogen:
- Synthesized peptide derived from human EI24 AA range: 107-157
- Specificity:
- This antibody detects endogenous levels of EI24 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 37kD
- Background:
- This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014],
- Function:
- induction:By TP53/p53.,similarity:Belongs to the EI24 family.,
- Subcellular Location:
- Nucleus membrane ; Multi-pass membrane protein . Cytoplasm . Endoplasmic reticulum membrane ; Multi-pass membrane protein .
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night