• Target：
• EI24

• Fields：
• >>p53 signaling pathway

• Gene Name：
• EI24 PIG8

• Protein Name：
• EI24

• Human Gene Id：
• 9538

• Human Swiss Prot No：
• O14681

• Mouse Gene Id：
• 13663

• Mouse Swiss Prot No：
• Q61070

• Rat Gene Id：
• 300514

• Rat Swiss Prot No：
• Q4KM77

• Immunogen：
• Synthesized peptide derived from human EI24 AA range: 107-157

• Specificity：
• This antibody detects endogenous levels of EI24 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 37kD

• Background：
• This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014],

• Function：
• induction:By TP53/p53.,similarity:Belongs to the EI24 family.,

• Subcellular Location：
• Nucleus membrane ; Multi-pass membrane protein . Cytoplasm . Endoplasmic reticulum membrane ; Multi-pass membrane protein .

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