• Target：
• SUSD2

• Gene Name：
• SUSD2

• Protein Name：
• SUSD2

• Human Gene Id：
• 56241

• Human Swiss Prot No：
• Q9UGT4

• Mouse Gene Id：
• 71733

• Mouse Swiss Prot No：
• Q9DBX3

• Immunogen：
• Synthesized peptide derived from human SUSD2 AA range: 666-716

• Specificity：
• This antibody detects endogenous levels of SUSD2 at Human/Mouse

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 90kD

• Function：
• similarity:Contains 1 AMOP domain.,similarity:Contains 1 SMB (somatomedin-B) domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,similarity:Contains 1 VWFD domain.,

• Subcellular Location：
• Cell membrane ; Single-pass type I membrane protein . SUSD2 and LGALS1 co-localized in very specific, punctate regions along the cell membrane of breast cancer cells. .

• Expression：
• Highly expressed in breast cancer, but shows a restricted expression pattern in normal tissues such as adipose, adrenal gland, kidney, lung, mammary gland, placenta, thyroid, trachea, and uterus (PubMed:23131994). Also expressed in colon; down-regulated in colon cancer tissues (PubMed:25351403).

TRPC4 aggravates hypoxic pulmonary hypertension by promoting pulmonary endothelial cell apoptosis FREE RADICAL BIOLOGY AND MEDICINE Liu Yang WB Mouse lung tissue pulmonary arterial endothelial cell (PAEC)

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