NBPFG rabbit pAb
- Catalog No.:YT6753
- Applications:WB;IHC
- Reactivity:Human;Rat;Mouse;
- Target:
- NBPFG
- Gene Name:
- NBPF16
- Protein Name:
- NBPFG
- Human Swiss Prot No:
- Q5SXJ2
- Immunogen:
- Synthesized peptide derived from human NBPFG AA range: 49-99
- Specificity:
- This antibody detects endogenous levels of NBPFG at Human
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 74kD
- Background:
- This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, May 2013],
- Function:
- miscellaneous:Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.,similarity:Belongs to the NBPF family.,similarity:Contains 10 NBPF domains.,similarity:Contains 2 NBPF domains.,similarity:Contains 3 NBPF domains.,similarity:Contains 6 NBPF domains.,similarity:Contains 7 NBPF domains.,similarity:Contains 8 NBPF domains.,tissue specificity:Expressed in a neuroblastoma cell line.,tissue specificity:Expressed in spinal cord.,tissue specificity:Expressed in spleen and fetal liver.,tissue specificity:Expressed in the mammary gland.,tissue specificity:Ubiquitously expressed with a higher expression observed in breast and liver. Also expressed in neuroblastoma cell line.,tissue specificity:Widely expressed. The only tissue which shows a weak expression is kidney.,
- Subcellular Location:
- cytoplasm,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- September 08-2020
- FLOW-CYTOMEYRT-PROTOCOL
- May 20-2022
- Cell-Based ELISA│解您多样本WB检测之困扰
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).