LIPT2 rabbit pAb

    • Catalog No.:YT6733
    • Applications:WB;IHC
    • Reactivity:Human;Mouse
      • Target:
      • LIPT2
      • Fields:
      • >>Lipoic acid metabolism;>>Metabolic pathways;>>Biosynthesis of cofactors
      • Gene Name:
      • LIPT2
      • Protein Name:
      • LIPT2
      • Human Swiss Prot No:
      • A6NK58
      • Mouse Swiss Prot No:
      • Q9D009
      • Immunogen:
      • Synthesized peptide derived from human LIPT2 AA range: 8-58
      • Specificity:
      • This antibody detects endogenous levels of LIPT2 at Human/Mouse
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 25kD
      • Background:
      • This gene encodes a mitochondrial protein that catalyzes the transfer of octanoic acid to lipoate-dependent enzymes such as octanoyl-ACP. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],
      • Function:
      • catalytic activity:Octanoyl-[acyl-carrier-protein] + protein = protein N(6)-(octanoyl)lysine + [acyl-carrier-protein].,function:Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.,miscellaneous:In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.,pathway:Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.,similarity:Belongs to the lipB family.,
      • Subcellular Location:
      • Mitochondrion .
      • Products Images
      • Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human lung cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).