FBX6 rabbit pAb
- Catalog No.:YT6731
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- FBX6
- Fields:
- >>Protein processing in endoplasmic reticulum
- Gene Name:
- FBXO6 FBG2 FBS2 FBX6
- Protein Name:
- FBX6
- Human Gene Id:
- 26270
- Human Swiss Prot No:
- Q9NRD1
- Mouse Gene Id:
- 50762
- Mouse Swiss Prot No:
- Q9QZN4
- Rat Gene Id:
- 192351
- Rat Swiss Prot No:
- Q923V4
- Immunogen:
- Synthesized peptide derived from human FBX6 AA range: 30-80
- Specificity:
- This antibody detects endogenous levels of FBX6 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 32kD
- Background:
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. [provided by RefSeq, Jul 2008],
- Function:
- function:Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.,online information:hFBG2,similarity:Contains 1 F-box domain.,similarity:Contains 1 FBA (F-box associated) domain.,subunit:Part of a SCF (SKP1-cullin-F-box) protein ligase complex.,
- Subcellular Location:
- Cytoplasm .
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from VEC cells, primary antibody was diluted at 1:1000, 4°over night