DDAH1 rabbit pAb
- Catalog No.:YT6722
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- DDAH1
- Gene Name:
- DDAH1 DDAH
- Protein Name:
- DDAH1
- Human Gene Id:
- 23576
- Human Swiss Prot No:
- O94760
- Mouse Gene Id:
- 69219
- Mouse Swiss Prot No:
- Q9CWS0
- Rat Gene Id:
- 64157
- Rat Swiss Prot No:
- O08557
- Immunogen:
- Synthesized peptide derived from human DDAH1 AA range: 115-165
- Specificity:
- This antibody detects endogenous levels of DDAH1 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 31kD
- Background:
- This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 2008],
- Function:
- catalytic activity:N(omega),N(omega)-dimethyl-L-arginine + H(2)O = dimethylamine + L-citrulline.,cofactor:Binds 1 zinc ion.,function:Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in nitric oxide generation.,similarity:Belongs to the DDAH family.,subunit:Monomer.,
- Subcellular Location:
- mitochondrion,cytosol,extracellular exosome,
- Expression:
- Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night