PRDM7 rabbit pAb

    • Catalog No.:YT6582
    • Applications:WB;ELISA;IHC
    • Reactivity:Human
      • Target:
      • PRDM7
      • Fields:
      • >>Lysine degradation;>>Metabolic pathways
      • Gene Name:
      • PRDM7 PFM4
      • Protein Name:
      • PRDM7
      • Human Swiss Prot No:
      • Q9NQW5
      • Immunogen:
      • Synthesized peptide derived from human PRDM7 AA range: 28-78
      • Specificity:
      • This antibody detects endogenous levels of PRDM7 at Human
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 54kD
      • Background:
      • This gene encodes a member of a family of proteins that may have roles in transcription and other nuclear processes. The encoded protein contains a KRAB (Kruppel-associated box) domain -A box and a SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain and may function as a histone methyltransferase. [provided by RefSeq, Aug 2013],
      • Function:
      • catalytic activity:S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N(6)-methyl-L-lysine.,function:Probable histone methyltransferase.,miscellaneous:The mouse orthologous protein seems not to exist. According to PubMed:17916234, human PRDM7 and PRDM9 genes, a pair of close paralogs corresponding to a single mouse gene Prdm9, were generated by a recent gene duplication event after the divergence of the ancestors of human and mouse.,similarity:Contains 1 KRAB-related domain.,similarity:Contains 1 SET domain.,
      • Subcellular Location:
      • Nucleus . Chromosome .
      • Products Images
      • Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).