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- EXTL2 rabbit pAb
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EXTL2 rabbit pAb
- Catalog No.:YT6504
- Applications:WB
- Reactivity:Human;Mouse
- Fields:
- >>Glycosaminoglycan biosynthesis - heparan sulfate / heparin;>>Metabolic pathways
- Immunogen:
- Synthesized peptide derived from human EXTL2 AA range: 141-191
- Specificity:
- This antibody detects endogenous levels of EXTL2 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 36kD
- Function:
- catalytic activity:UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.,function:Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.,online information:Exostosin-like 2,online information:GlycoGene database,pathway:Glycan metabolism; heparan sulfate biosynthesis.,PTM:The soluble form derives from the membrane form by proteolytic processing.,similarity:Belongs to the glycosyltransferase 47 family.,subcellular location:A soluble form is found in the serum.,tissue specifi
- Subcellular Location:
- Endoplasmic reticulum membrane ; Single-pass type II membrane protein .; [Processed exostosin-like 2]: Secreted. A soluble form is found in the serum.
![](/uploadfiles/PIC/YT6504wb-2019.jpg)
- Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night