EXTL2 rabbit pAb

    • Catalog No.:YT6504
    • Applications:WB
    • Reactivity:Human;Mouse
      • Target:
      • EXTL2
      • Fields:
      • >>Glycosaminoglycan biosynthesis - heparan sulfate / heparin;>>Metabolic pathways
      • Gene Name:
      • EXTL2 EXTR2
      • Protein Name:
      • EXTL2
      • Human Gene Id:
      • 2135
      • Human Swiss Prot No:
      • Q9UBQ6
      • Mouse Swiss Prot No:
      • Q9ES89
      • Immunogen:
      • Synthesized peptide derived from human EXTL2 AA range: 141-191
      • Specificity:
      • This antibody detects endogenous levels of EXTL2 at Human/Mouse
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 36kD
      • Function:
      • catalytic activity:UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.,function:Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.,online information:Exostosin-like 2,online information:GlycoGene database,pathway:Glycan metabolism; heparan sulfate biosynthesis.,PTM:The soluble form derives from the membrane form by proteolytic processing.,similarity:Belongs to the glycosyltransferase 47 family.,subcellular location:A soluble form is found in the serum.,tissue specifi
      • Subcellular Location:
      • Endoplasmic reticulum membrane ; Single-pass type II membrane protein .; [Processed exostosin-like 2]: Secreted. A soluble form is found in the serum.
      • Expression:
      • Ubiquitous.
      • Products Images
      • Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night